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  <front>
    <journal-meta id="journal-meta-1">
      <journal-id journal-id-type="nlm-ta">Biomedical Research and Therapy</journal-id>
      <journal-id journal-id-type="publisher-id">Biomedical Research and Therapy</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">http://www.bmrat.org/</journal-id>
      <journal-title-group>
        <journal-title>Biomedical Research and Therapy</journal-title>
      </journal-title-group>
      <issn publication-format="print"/>
    </journal-meta>
    <article-meta id="article-meta-1">
      <article-id pub-id-type="doi">10.15419/bmrat.v7i10.641</article-id>
      <title-group>
        <article-title id="at-8a454f514327">
          <bold id="strong-1">Clinical decision-making approaches by health caregivers of patients with COVID-19</bold>
        </article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid"/>
          <name id="n-2bedeb6b3cd7">
            <surname>Taghadosi</surname>
            <given-names>Mohsen</given-names>
          </name>
          <xref id="x-204dbc4d6aa3" rid="a-2325c40fa862" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid"/>
          <name id="n-20f72c158314">
            <surname>Ajorpaz</surname>
            <given-names>Neda Mirbagher</given-names>
          </name>
          <xref id="x-285a280d3320" rid="a-a7dba173be9b" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <contrib-id contrib-id-type="orcid">0000-0001-9776-4936</contrib-id>
          <name id="n-da068f98ef88">
            <surname>Aghajani</surname>
            <given-names>Mohammad</given-names>
          </name>
          <email>aghajani1362@yahoo.com; aghajani_m@kaums.ac.ir</email>
          <xref id="x-8b4bf98d0561" rid="a-ea08a8624533" ref-type="aff">3</xref>
        </contrib>
        <aff id="a-2325c40fa862">
          <institution>Trauma Nursing Research Center, Department of Medical Surgical Nursing, School of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, IR Iran</institution>
        </aff>
        <aff id="a-a7dba173be9b">
          <institution>Autoimmune Diseases Research Center, Department of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Iran</institution>
        </aff>
        <aff id="a-ea08a8624533">
          <institution>Infectious Diseases Research Center, Department of Psychiatric Nursing, Kashan University of Medical Sciences, Kashan, IR Iran</institution>
        </aff>
      </contrib-group>
      <volume>7</volume>
      <issue>10</issue>
      <permissions/>
      <abstract id="abstract-8fdf91a0c479">
        <title id="abstract-title-56ae8f720aea">Abstract</title>
        <p id="paragraph-a5c9b9e3db1f">The Coronavirus disease of 2019 COVID-19) is the current health crisis in the world- a new, complex phenomenon that has affected and hospitalized many people around the world. Health care providers deal with COVID-19 patients daily and care for the patients while there is no definitive cure for it. Clinical decision-making is an important task of health professionals that plays an essential role in preserving the patient's life and providing quality care. Therefore, understanding clinical decision-making approaches by healthcare providers, such as nurses and physicians, especially in crises such as COVID-19, is essential.</p>
        <p id="p-6acd5caafd79"/>
      </abstract>
      <kwd-group id="kwd-group-1">
        <title>Keywords</title>
        <kwd>Clinical decision making</kwd>
        <kwd>COVID-19</kwd>
        <kwd>health care providers</kwd>
        <kwd>intuition</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec>
      <title id="t-33053a8e5dfb">Introduction </title>
      <p id="p-59446c8a049d">The Coronavirus disease of 2019 (COVID-19) pandemic is the current health crisis in the world<xref id="x-f1e1b181e760" rid="R90626420524977" ref-type="bibr">1</xref>. The pandemic has affected people of all nations, continents, races, and socioeconomic groups<xref id="x-0543877b55ee" rid="R90626420524978" ref-type="bibr">2</xref>. By September 08, 2020, about 27,332,199 patients in the word were affected by severe acute respiratory syndrome, about 893,700 nationwide deaths had been reported due to COVID-19, about 19,410,434 COVID-19 patients had recovered and were discharged from hospitals, and more people with severe conditions were still hospitalized (WHO, 2020).  Despite worldwide preventive measures, as well as individual and public precautions, significant numbers of people were still infected, hospitalized, and dying around the world. The global COVID-19 mortality rate is between 3% and 15%<xref id="x-a5c01d4ceb6a" rid="R90626420524977" ref-type="bibr">1</xref>. </p>
      <p id="p-3adf4bc6e225"/>
      <p id="p-daf7fe5f25b1">The treatment team includes nurses and physicians as the front line of care, and their quality of practice is a meaningful indicator of quality of care across healthcare systems<xref id="x-c8d8c26e7595" rid="R90626420524980" ref-type="bibr">3</xref>. They provide a substantial role in the care of COVID-19 patients. However, there is no guideline for patient care and clinical decision-making for nurses during the COVID-19 crisis.</p>
      <p id="p-e9c02a27ab3d"/>
      <p id="p-69783a4470e7">Clinical decision-making is a phenomenon that is fundamental to healthcare practice. It influences the entire spectrum of healthcare practitioners and nurses as frontline clinicians are faced with important clinical decisions on a daily basis<xref id="x-da9902751410" rid="R90626420524983" ref-type="bibr">4</xref>. The overall goal of clinical decision-making is to provide the highest quality of patient care based on the available resources. Nurses are accountable for saving lives of patients,<italic id="emphasis-1"> </italic> the general public, the profession, and the organizations in which they work. Therefore, it is essential to have an understanding of their clinical decision-making approaches, especially in crises such as COVID-19. </p>
      <p id="p-a1dd640021ce"/>
      <p id="p-1ea4addf2cd8">In the literature, two models of decision-making have been widely recognized: the information-processing model (analytical model) and the intuitive-humanist model (intuitive model)<xref id="x-3f876a475eb9" rid="R90626420524985" ref-type="bibr">5</xref>. Analytical thinking is a logical and linear model of thinking that focuses on objective data. Intuitive thinking is an unconscious process that occurs rapidly and is rooted in experience and emotion<xref id="x-09f70bf8c3bd" rid="R90626420524986" ref-type="bibr">6</xref>. Researchers have indicated that relying on intuition in decision-making can be more effective, reliable, and trustworthy compared to using objective data and logical thinking. They believe that the outcomes of intuitive thinking are comparable with analytical thinking, but information processing and cognitive efforts in intuitive thinking are faster and more efficient<xref rid="R90626420524987" ref-type="bibr">7</xref>, <xref rid="R90626420524988" ref-type="bibr">8</xref>. In life-threatening conditions and crises, as well as situations wherein there is a need for creativity and innovation, nurses use intuition in their decision-making. Evidence also indicates that in complicated clinical situations due to ethical conflicts, nurses benefit from intuition for moral decision-making and best practices<xref id="x-e06c1dbd211d" rid="R90626420524989" ref-type="bibr">9</xref>. Therefore, in critical health conditions, intuition is essential for caregivers to improve quality of care, manage crises, and diagnose patients’ conditions, as well as to help reduce mortality rates<xref id="x-92c43aeee624" rid="R90626420524990" ref-type="bibr">10</xref>. Currently, nurses around the world are dealing with COVID-19, a disease that continuously demonstrates a variety of unknown and newly-known features. In this condition, because of a lack of knowledge and clinical guidelines, nurses’ clinical decision-making and use of intuition in their decision-making play an important role in management of the disease outcomes and community health. Clinical decision-making methods are especially important in critical care units. For example, among ICU nurses who provide care for severely ill or injured patients, accuracy and speed are exclusively crucial, which should be considered in clinical decision-making and practice<xref id="x-d7b8fbaa0166" rid="R90626420524991" ref-type="bibr">11</xref>. </p>
      <p id="p-d89eab1d03bc"/>
      <p id="p-d5f9cfdb33dc">Nursing practice related to COVID-19 is a new experience; thus, there is a lack of knowledge about approaches of clinical decision-making. Intuition is recognized as an important type of knowledge and a valid method of knowledge in clinical practice. Indeed, intuition is linked to improved clinical judgment, effective decision-making, and overcoming crises. Taking all the statements into account, in novel and complex conditions, such as the COVID-19 crisis where there is a lack in knowledge, intuition can be used to improve clinical decision-making. To realize and use intuition in clinical decision-making practices, we need to examine the process and how it is used in critical situations in the clinic, integrating live experiences into the body of knowledge, and developing theories to describe it. Therefore, the attention of researchers and clinical managers should be increasingly drawn to this important decision-making approach in the care of COVID-19 patients.</p>
      <p id="p-939c4ec15c74"/>
    </sec>
    <sec>
      <title id="t-8215e65db523">
        <bold id="s-0853670724d4">Abbreviations</bold>
      </title>
      <p id="p-97f09288032f"><bold id="s-691d9a065722">COVID-19</bold>: Coronavirus disease 2019</p>
      <p id="p-4e1bdf604947"/>
    </sec>
    <sec>
      <title id="t-1c43c79e00d6">
        <bold id="s-e71274db9ee8">Acknowledgments </bold>
      </title>
      <p id="p-6d5be7bdcec0">This study approved by the Research Deputy of  Kashan University of Medical Sciences, Grant No: 98102. The researchers would like to express their gratitude to the nurses of hospitals of Kashan, Iran.</p>
      <p id="p-a5fb47f9797b"/>
    </sec>
    <sec>
      <title id="t-74bf2b9bf4c8">
        <bold id="s-62f2e283ed47">Author’s contributions</bold>
      </title>
      <p id="t-14b0b4c08504">All authors equally contributed in this article. All authors read and approved the final manuscript. </p>
      <p id="p-6f3bc41c84ef"/>
    </sec>
    <sec>
      <title id="t-8a9bb5e6f51f">
        <bold id="s-44297992aa59">Funding</bold>
      </title>
      <p id="t-e9e02c9ee507">None.</p>
      <p id="p-aed385352828"/>
    </sec>
    <sec>
      <title id="t-32d106ec8040">
        <bold id="s-692ad76a16dd">Availability of data and materials</bold>
      </title>
      <p id="t-8a46e7b596a5">Not applicable.</p>
      <p id="p-0a53d799f565"/>
    </sec>
    <sec>
      <title id="t-c506824cc575">
        <bold id="s-7d5c7ef2e3c1">Ethics approval and consent to participate</bold>
      </title>
      <p id="t-21f3965ef581">Not applicable.</p>
      <p id="p-50dbc499c718"/>
    </sec>
    <sec>
      <title id="t-7b11992b8dba">
        <bold id="s-0d9d5cc2e34d">Consent for publication</bold>
      </title>
      <p id="t-554e965856fa">Not applicable.</p>
      <p id="p-9af43953a1ab"/>
    </sec>
    <sec>
      <title id="t-e51ae3f112ad">
        <bold id="s-5d7eb849f4af">Competing interests</bold>
      </title>
      <p id="t-e0f7aae55020">The authors declare that they have no competing interests.</p>
      <p id="p-f39c0b567465"/>
    </sec>
  </body>
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